Recognizing that that science, technology, engineering, and math (STEM) education is key to the future of the region’s youth, we began to introduce STEM-focused programming designed to equip young learners with knowledge and skills that will help them better respond to the changing needs of the global economy and contribute to their countries’ economic development through innovative ideas that create impact. An important milestone was the establishment — with generous funding from Boeing — of the STEM Center at Amideast/Cairo, offering inquiry-based learning programs that foster creativity and problem-solving skills in STEM through experimentation and inquiry-based learning programs.